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Poster presentations / European Geriatric Medicine 6S1 (2015) S32

S156

S137

was benzodiazepine (taken for ≥4 weeks; increase the risk of fall)

and use of proton pump inhibitor.

START detected 48 potential prescribing omissions in 44 patients.

Calcium-vitamin D supplementation in osteoporosis was the

most frequent (40%). Omissions corresponding to vaccines

(Pneumococcal vaccine) and the cardiovascular system involving

25% and 30% of patients respectively.

Conclusion:

The STOPP-START criteria reveal that pre-admission

PIM use is highly prevalent among elderly patients, the most

frequently was benzodiazepine. The prescribing omissions detected

by the START criteria require intervention.

P-392

STOPP/START criteria version 2 and 2012 Beers’ criteria:

Are they complementary?

E.H. Azana Fernandez

1

, Y.R. Davila Barboza

1

1

Hospital San Juan de Dios, Le´on, Spain

Introduction:

Some important essential differences between

STOPP/START and Beers criteria remain, principally the list of START

criteria and the avoidance of mention of some Beers criteria drugs

that are now absent from most European drug formularies

Objectives:

Assess the prevalence of potentially inappropriate

medication use in older people.

Method:

We retrospectively studied patients hospitalised at

Geriatric Department during October to November 2014. Diagnoses

and pre-admission medication were recorded.

Results:

100 patients were included, mean patient age was

85.26

±

5.4 years. 72% were female. Mean Charlson’s index: 1.97.

Mean number of prescription medicines: 7.9. Polypharmacy

(≥5 drugs): 76%. Excessive polypharmacy (≥10 drugs): 38%.

Potentially inappropriate medications (PIMs): STOPP identified 94

PIMs affecting 70 patients, the most frequently encountered PIM

was benzodiazepine (taken for ≥4 weeks; increase the risk of fall)

and use of proton pump inhibitor. Beer’s criteria identified 51 PIMs

affecting 36 patients, the most frequently encountered PIM was

short-intermediate acting benzodiazepine.

The correlation between both criteria was weak, with a Kappa

index of 0.22.

Conclusion:

Pre-admissi ´on PIM use is highly prevalent among

elderly patients, the most frequently was benzodiazepine. Because

the majority of criteria PIMs do not overlap in Beers and STOPP,

both list could be complementary.

P-393

Quality of pharmacotherapy in old age: focus on lists of

Potentially Inappropriate Medication (PIM lists). Results from

the European Science Foundation exploratory workshop

M. Azermai

1

, R. Vander Stichele

2

, M. Elseviers

2

1

Ghent University, Gent, Belgium;

2

Ghent University, Heymans

Institute of Pharmacology, Division of Clinical Pharmacology, Gent,

Belgium

Objectives:

On June 12–14, 2014, experts gathered in Ghent,

Belgium, for a European Science Foundation workshop on

pharmacotherapy in old age, aiming to define the requirements

for electronic assessment of Potentially Inappropriate Medication

(PIM) lists.

Methods:

15 experts from 8 European countries. The program

consisted of 5 sessions: conceptual framework; repository of

PIMs out of existing lists of PIMs; identification of PIMs suitable

for electronic assessment based on routinely collected data;

relationship with quality indicators; international collaboration.

Draft recommendations were proposed based on the panel

discussions, which were again discussed by the experts to achieve

consensus for the final recommendations.

Results:

The experts agreed that a repository should be

maintained of all existing PIMs, which are part of at least one

existing list, and which have undergone efforts of validation of

their contents. PIMs suitable for electronic, broad, and regular

evaluation of pharmacotherapy should be identified, with the

distinction between drug-oriented and more clinically oriented

PIMs. Prerequisites for electronic assessment involve precise

codification of medication, clinical data and the decision rules to

permit secondary use of routinely collected clinical data in specific

settings and on national as well as international level. Throughout

the development of PIMs, researchers should consider their

suitability for electronic application and semantic interoperability.

Conclusion:

PIM lists are mainly used in research settings or in

preparation of medication chart reviews. The requirements for

automated electronic use of PIMsin routine auditing of the quality

of pharmacotherapy in old age are yet to be fulfilled in most

countries.

P-394

Potentially inappropiate use of drugs in patients attending

a geriatric day hospital

E. Baeza-Monedero

1

, E. De Jaime

2

, P. Fern ´andez-Montalb ´an

1

,

C. S ´anchez Castellano

1

, A.J. Cruz-Jentoft

3

, R. Miralles

2

1

Hospital Ram´on y Cajal, Madrid, Spain;

2

Parc de Salut Mar

Centre

Forum, Barcelona, Spain;

3

Hospital Universitario Ram´on y Cajal,

Madrid, Spain

Objectives:

To describe potentially inappropriate prescriptions

before and after an intervention in a Geriatric Day Hospital (GDH).

Material and Methods:

We reviewed retrospectively the clinical

records of all patients discharged from a Geriatric Day Hospital in

one year. Drug treatment was assessed at the times of admission

and discharge, using 2014 STOPP-START criteria.

Results:

139 subjects included, mean age 80. On admission,

97 (69.8%) met at least one STOPP criteria. The most common

criteria were: use of full-dose PPIs for more than 8 weeks

(49.6%), use of drugs that increase the risk of falls (24.8%),

benzodiazepines for more than 4 weeks (24.1%) and use of long-

term NSAIDs for the symptomatic treatment of osteoarthritis (5.6%).

At admission, 40 patients met at least one START criteria (28.8%);

the most prevalent were: lack of antiresorptive treatment or bone

anabolic steroids in patients with known osteoporosis (8.5%), lack

of calcium supplements and vitamin D (5.6%) and non-use of

acetylcholinesterase inhibitors for mild to moderate Alzheimer’s

disease or dementia with Lewy bodies (4.2%).

At GDH discharge, the most frequent STOPP criteria was still the use

of PPIs without a clear indication (42.5%) and the most frequent

START criteria was not using antiresorptive or anabolic bone in

osteoporosis (4.2%).

Conclusion:

The most prevalent inappropriate drug treatment in

patients attending a GDH was the chronic use of PPI for more than

8 weeks, and this was not improved at GDH discharge.

P-395

Inappropiate use of drugs before and after an intervention

in a geriatric day hospital

E. Baeza-Monedero

1

, E. De Jaime

2

, J. Alb ´eniz-L ´opez

3

, B. Montero-

Errasqu´ın

1

, A.J. Cruz-Jentoft

4

, R. Miralles

2

1

Hospital Ram´on y Cajal, Madrid, Spain;

2

Parc de Salut Mar

Centre

Forum, Barcelona, Spain;

3

Ram´on y Cajal, Madrid, Spain;

4

Hospital

Universitario Ram´on y Cajal, Madrid, Spain

Objective:

To study the prevalence of inappropriate prescriptions

before and after an intervention in a Geriatric Day Hospital (GDH).

Material and Methods:

We reviewed retrospectively the clinical

records of all patients discharged from a Geriatric Day Hospital in

one year. Drug treatment was assessed at the times of admission

and discharge, using 2014 STOPP-START criteria.

Results:

139 subjects were included, mean age 80. The mean

number of STOPP criteria at admission was 1.93

±

1.09, reduced at