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S142

Poster presentations / European Geriatric Medicine 6S1 (2015) S32

S156

was actually lower in patients using statins compared with patients

not using statins.

Conclusions:

In the general population of elderly patients beyond

the age of 80 statin therapy is not associated with reduced

mortality, and in well-nourished patients beyond the age of 86

this therapy might be even associated with lower survival.

P-410

Potential glycemic overtreatment in patients admitted to the

geriatric ward

A. Kasiukiewicz

1

, Z.B. Wojszel

1

, K. Klimiuk

2

, A. Wojskowicz

1

1

Medical University of Białystok, Białystok, Poland;

2

ZOZ MSW

Hospital in Białystok, Białystok, Poland

Objectives:

The aim of the study was to identify high-risk of serious

hypoglycemia patients who had evidence of intensive glycemic

treatment.

Methods:

Cross-sectional study of patients hospitalized in 2009–

2010 with a diagnosis of type 2 diabetes, and receiving insulin

and/or oral antidiabetic drugs before hospitalization. Intensive

glycemic control was defined as the hemoglobin A1C level (HbA1C)

less than 6.0%, less than 6.5%, or less than 7.0% at admission. The

primary outcome measure was an HbA1C less than 7.0% in patients

who were aged 75 years or older, who had a diagnosis of cognitive

impairment or dementia, or who had end-stage renal disease –

GFR

<

30ml/min/1.73m

2

.

Results:

There were 213 diabetic patients, who received insulin

or oral antidiabetic agents before hospitalization, with an HbA1c

test result documented in the medical record. 65.7% received

sulfonurea, 39.1% metformin, 30.9% insulin, and 3.9% acarbose

(34.3% received sulfonurea alone, 20% sulfonurea with metformin,

7.4% sulfonurea with insulin, 16.1% insulin alone, 4.8% insulin with

metformin, and 12.2% metformin alone). No other glucose lowering

medications were reported.

We identified 66 patients (31%) as the denominator for the primary

outcome measure; 43.9% had a HbA1C value less than 6.0%, 54.5%

less than 6.5%, and 69.7% less than 7.0%.

Conclusions:

Patients with risk factors for serious hypoglycemia

represent a large subset of individuals receiving hypoglycemic

medications admitted to a geriatric ward; almost three fourth of

them had evidence of intensive treatment and it pointed to the

need for more diabetes treatment control in this group.

P-411

Prescriptions’ modifications in atrial fibrillation patients before

and after admission to Geriatrics department. Facts and Myths

A. Kearney-Schwartz

1

, M. Picard

2

, C. Perret-Guillaume

2

, E. Alliot

2

,

A. Benetos

3

1

University Hospital of Nancy, Vandoeuvre-l`es-Nancy, France;

2

CHU

Nancy, Vandoeuvre-l`es-Nancy, France;

3

France

Introduction:

Atrial Fibrilation (AF) concerns 9% of the population

over 75 years old and its prevalence increases with age.

Recommendations on the use of anticoagulants are made upon

the balance of hemorrhagic and thrombotic risk factors scores.

Nevertheless the best choice remains difficult.

The aim of this study is to describe the AF management before

and after admission to Geriatrics department and to identify the

criteria influencing the therapeutic decisions.

Methods:

This retrospective study was performed on the 2012 data

of the Geriatric Dept. of the Nancy University Hospital. All patients

hospitalized during this year, with a history of AF in discharge letter

were included in this analysis. The treatment data were collected

at admission and at discharge of the hospitalisation.

Results:

Among 126 patients (women 66.7%; mean age 85.6

±

5.9),

51.6% were receiving an anticoagulants at admission and 60.3%

at the end of hospitalisation. Very few of them (2.4% and

0.8%, respectively) received a novel oral anticoagulant (NOA). The

patients were treated by anti-arrhythmic agent in 65.9% at the

beginning and 71.4% at the end, mostly by beta blocker.

Conclusions:

Most of the patients were receiving anticoagulants

drugs. Among them the vast majority were receiving anti-Vitamin K

drugs and very few NOA. The prescription of anti-arrhythmic drugs

depends mostly on patients’ co-morbidity and doctor’s experience.

The on-going studies on NOA will provide more data concerning

the efficacy and the safety of this new class.

P-412

Vitamin D testing in older adults with falls and fracture is

a must

Y. Latief

1

, C. Lisk

2

1

Potters Bar hospital, hertfordshire community NHS trust, London,

United Kingdom;

2

Barnet hospital, Royal free NHS foundation Trust,

London, United Kingdom

Introduction:

Vitamin D deficiency (vdd) is common in older

adults who often have less sun exposure. Vdd is associated with

poor muscle function and bone pain. Birschoff ferrari et al 2009

concluded that vitamin d supplements can reduce the risk of falls

by 19% in persons over the age of 65 years. Given this, we looked at

the correlation between vdd and fracture in a cohort of older adults

receiving rehabilitation in an inpatient united kingdom community

hospital setting.

Methods:

Medical records of patients admitted with falls from

January 2012 to December 2013 were analysed. Demographics, risk

factors for falls, fracture type and vitamin d levels were collated;

diagnosis was according to institute of medicine thresholds;

deficiency

<

30 nmol/l (vdd), insufficiency 30–50 nmol/l (vdi).

Results:

200 patients out of 607 patients were identified. There

was a female predilection (114). The age range was 60–95

years. The commonest risk factors were polypharmacy, sepsis and

dementia. 74 (37%) had vdd, 54 (27%) had vdi whilst 72 (36%) had

adequate vitamin D levels. 151/200 patients sustained a fracture;

the commonest fracture being fracture neck of femur (75) with

fractures of the ankle (19), pubic rami (17), femur (10), elbow (7),

humerus (6), wrist (5), tibia (4) and others (8) accounting for the

rest. 89/151 (59%) patients who had a fracture had vdd.

Conclusion:

Vdd and vdi is highly prevalent in older patients with a

fracture. It is therefore important that all older adults with fractures

having rehabilitation are screened and treated to maximise the

benefits of rehabilitation.

P-413

Correction of Vitamin D and parathyroid hormone

concentration (PTH) in patients with acute hip fracture and low

25 hydroxy-vitamin D. Results at 3 months by a replenishment

protocol

R. Men ´endez

1

, T. Alarcon

1

, J.I. Gonz ´alez-Montalvo

1

, P. Gotor

1

,

I. Mart´ın-Maestre

1

1

Hospital Universitario La Paz, Madrid, Spain

Objective:

To known the effectiveness of a replenishment protocol

in the correction of vitamin D levels in hip fracture (HF) patients

with vitamin D deficiency.

Method:

Patients aged 65 and over consecutively admitted with HF

between 25th January 2013 and 26th February 2014 and enough

fit as to be followed-up in the ambulatory office were included.

Besides of demographic, clinical, and geriatric assessment variables,

vitamin D and PTH levels were assessed at admission and three

months after discharge.

Results:

We studied 134 patients with a mean age of 82.9

years (DS 6.3), 80.6%. Female. The fracture was extracapsular

in 73 (54.5%) patients. At admission, 127 patients (94.5%) had

25OHD

<

31 ng/ml, and 98 (73.1%) had 25OHD

<

20 ng/ml. Fifty-

two (39.1%) had secondary hyperparathyroidism (SHPT). Patients

with vitamin D

<

21 ng/ml received 180,000 IU Calcifediol per os