European Geriatric Medicine - Supplement 1 - Volume 6 - September 2015

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S86 Poster presentations / European Geriatric Medicine 6S1 (2015) S32–S156
incident mobility impairment. However, mortality risk patterns
were inconsistent and further validation of their cut-off points
in other populations seems needed (McLean et al., 2014 Journals of
Gerontology).
In this study, we aimed to evaluate the FNIH cut-off points for
weakness and low muscle mass in a sample of community-dwelling
older men in Belgium.
Methods: This community-based cohort study included 200
ambulatory men aged ≥74, living in the community of Merelbeke
(municipality of Ghent, Belgium).
Grip strength was measured twice consecutively using a Jamar type
dynamometer. Weakness was defined as low grip strength (<26 kg)
and low grip strength-to-body mass index [BMI] ratio (<1.00). Low
muscle mass (dual-energy x-ray absorptiometry) was categorized
as low appendicular lean mass [ALM] (<19.75 kg) and low ALM-to-
BMI ratio (<0.789).
Results: Mean age was 78.5(±3.5) years. Combined weakness and
low muscle mass was present in 4 to 9% of men, depending on
the criteria applied. After 12 years of follow-up, 134 men (67%)
had died. Low grip strength (HR = 1.59, 95% CI 1.06–2.28), low grip
strength-to-BMI ratio (HR = 1.65, 95% CI 1.03–2.65) and low ALM-
to-BMI ratio (HR = 1.68, 95% CI 1.18–2.41), but not low ALM, were
associated with all-cause mortality in older community-dwelling
men.
Conclusions: These findings confirm the FNIH cut-off points for
low grip strength and low ALM-to-BMI ratio as candidate criteria
for clinically relevant weakness and low muscle mass in men.
P-205
Discriminating sarcopenia and robustness: a matter of speed
limit
A.-M. De Cock1, M. Vandewoude2
1Hospital St Maarten Mechelen, University of Antwerp, Willebroek,
Belgium; 2Belgium
Sarcopenia definitions and cut-off points for each parameter were
formulated in 2011 by the European Working Group on Sarcopenia
in Older People (EWGSOP) and International working Group on
Sarcopenia (IWGS). These guidelines on diagnosis algorithm include
usual gait speed as the easiest and most reliable way to start
case finding. The EWGSOP stated a cut-off of <80 centimetres per
second (cm/s) to identify sarcopenia risk. IWGS put forward a speed
lower than 100 cm/s.
Aim: We want to define if either speed limit differentiates better
between robust and non-robust elderly.
Method: Participants were categorized robust or non-robust
according to their individual speed compared with normative
reference age and sex specific gait speed cut to define robust from
a cross-sectional study of non-disabled, non-demented elderly.
The reference persons were labelled robust when medically and
functionally stable over a period of 1 year. Our community dwelling
participants (day clinic patients and their relatives, patients recently
discharged from hospital) were able to walk 10 meters over a
Gaitrite System without help, had no clinical gait abnormalities,
used no walking aid or had no orthopaedic prosthesis.
Results: 171 participants (72% females and 28% males), age 70 to
89 years were identified as robust in 38% of the cases. Cohen’s
Kappa Measurement of agreement between the groups Robust
and Sarcopenia limit above 80 cm/s was 0.833 (Std Error 0.042,
P ≤ 0.0001). Kappa agreement determining Robust in the same
group as Sarcopenia limit over 100 cm/s was 0.576 (Std Error 0.062,
P ≤ 0.001).
Conclusion: Robustness matches up best with Sarcopenia criteria
using 80 cm/s as case finding limit in a random cohort.
P-206
Explicative factors of fear of fall in elderly. FISTAC Study
M. Esbr´ı, M. Mart´ınez, I. Huedo, M. L ´opez, I. Soler, A. Noguer ´on,
G. Sanchez, P. Abizanda
Department of Geriatrics, Complejo Hospitalario Universitario de
Albacete, Spain
Objective: Find out the factors associated with Fear of Falling
Syndrome (FoF) measured by the Falls Efficacy Scale – International
(FES-I) in patients included in the FISTAC study.
Methods: 52 patients included in FISTAC study. Variables: age,
gender, scales of Barthel, Lawton, FAC, Yesavage, MMSE, Charlson,
MNA-SF; fragility (Linda Fried criteria), polypharmacy, vitamine D,
SPPB, handgrip, legpress, limits of stability through posturography
and gait parameter through GAITRite system. The association
between this variables and FES-I was studied with correlation and
multiple linear regression tests.
Results: Mean age 78.7 years. 80.8% women. FES-I 31.4 (DE: 11.2).
67% presented FoF by FES-I. Mean of Barthel 92.1 (DE: 7.8);
Lawton 5.8 (DE: 2.3); MMSE 21.6 (DE: 4.5); Yesavage 5.3 (DE: 3.8);
drugs mean 7.9 (DE: 3.9); gait speed 4m: 0.63m/s (DE: 0.49);
SPPB 7.8 (DE: 2.7); 1RM legpress 67.3 kg (DE: 24.1); power
max legpress 150.9W (DE: 86.5); maximum excursion limits of
stability 56.9% (DE: 15). The multiple linear regression model
with the variables with significant correlation, evinced a corrected
r2 0.721. The variables independently associated with the FES-
I were: Barthel (B = −0.71, 95% CI −1.0 to −0.3, p< 0.001), Lawton
(B = 1.32, 95% CI 0.01–2.63, p < 0.05), FAC (B = 9.75, 95% CI 3.9–15.6,
p = 0.002), Yesavage (B = 0.76, 95% CI 0.17–1.34, p = 0.01), dizziness
(B = 6.02, 95% CI 1.89–10.16, p = 0.006), 1RM legpress (B = −0.16,
95% CI −0.31 to −0.01, p < 0.05), maximum excursion (B = −0.5, 95% CI
−0.82 to −2.18, P = 0.003), endpoint excursion (B = 0.38, 95% CI 0.03–
0.73, p = 0.04); global maximum power (B = 0.16, 95% CI 0.06–0.26,
p = 0.003).
Conclusions: The FoF in elderly measured by the FES-I scale, is
related to physical parameters such as muscle strength and power
in legpress, with the limits of stability, functional parameters
(Barthel, Lawton and FAC), with the scale Yesavage, and the
presence of dizziness.
P-207
Evaluation of the hypophyseal function in elderly patients
in a geriatric medicine unit
B. Gamboa Huarte1, I. Ferrando Lacarte 1, C. Deza Perez1,
M.M. Gonzalez Eizaguirre1 , C.M. Bibi ´an Getino1
1Hospital Nuestra Se˜nora de Gracia, Zaragoza, Spain
Objectives: To analyse the prevalence of functional disorders of the
hypophysis in elderly inpatients with an acute disease; which drugs
are related with the modification of the levels of prolactine and its
relationship with frailty determiners.
Methods: Descriptive, prospective, transversal study. Patients
with inpatient care from June to November 2014. Analysed
variables: sociodemographic, medical background (MB), usual
drugs, functional assessment (Barthel index, IB), cognitive
assessment, comorbidity (Charlson Index, CI), biochemical
parameters, hypophysiary hormones and inpatient death. SPSS
software package.
Results: 318 patients. 68.2% female. Mean age 86.31.
Emergency 84%. MB: cardiovascular 82.4%, neurological 61.3%,
dementia 43.1%, nephro-urological 40.6%, sensory 30.6%,
pulmonary 28.3%, thyroid disorders 10.7% (hypothyroidism 76.6%).
MDRD-GFR <60ml/min: 23% before admission, 45% in inpatient
blood test. IB < 45 in 37% in admission, 53.1% in discharge.
Anaemia 67.6%, low albumin 56.9%, high TSH 11%, high prolactin
in 33% of the patients. Inpatient death: 16%. In admission:
CI ≥ 5 18.6%, CI ≥ 3 46.9%, in discharge CI ≥ 3 55.5%. We found
significant associations among high prolactin levels and previous