100 / 210
S92
Poster presentations / European Geriatric Medicine 6S1 (2015) S32
–
S156
Mean FA score was −20.77
±
22.29 and HGS values were 16.55
±
8.54
in the whole group. FA score was −24.18
±
23.09 in patients with
dynapenia and −6.71
±
10.94 in non-dynapenics. Patients with low
FA scores were significantly higher in dynapenic patients versus
non-dynapenics (80.3% vs 19.7%).
Conclusion:
Dynapenia is common in elderly patients. FA scores
were significantly lower in dynapenic individuals. ‘The Functional
Autonomy Measurement System’ may be used for measuring
functional autonomy in a structured manner which allows using
scores.
P-226
Correlates of poor physical performance in older subjects with
comorbidity
A. Skalska
1
, M. Fedyk-Lukasik
2
, P. Fatyga
2
, T. Grodzicki
3
1
Jagiellonian University Medical College, Krakow, Poland;
2
Jagiellonian
University Medical College, Department of Internal Medicine and
Gerontology, Krakow, Poland;
3
Poland
The aim of the study:
To characterize factors associated with
different forms of physical impairments.
Methods:
In subjects aged 53–96 years comprehensive geriatric
assessment (MMSE, GDS, MNA, ADL, IADL) was performed.
Blood sample for standard laboratory tests and inflammatory
markers (hsCRP, osteoprotegerin (OPG), pantraxin3 (PTX3), IL-6,
IL-18, soluble receptor2 for TNFalfa (sTNFR2) were taken. Body
composition was measured by DXA. Gait speed, Timed Up&Go
test, 6-Minute Walk Test and handgrip strength was assessed.
Subjects were compared according to performance: gait speed
≥0.8m/s vs
<
0.8m/s, TUG
>
13.5 s vs ≤13.5 s, 6MWT ≥400 vs
<
400m
and handgrip
<
26 kg for men and
<
16 kg for women vs ≥26 and
≥16 kg respectively.
Results:
Mean age of 73 patients (65.8% men) was 70.7
±
8.4 yrs.
Mean number of diseases was 5.2
±
2.0, mean number of used
medications was 7.3
±
2.5.
Subjects who performed worse all physical tasks were older, had
higher OPG level, and had troubles in IADL. Poorly performed tasks
related to gait were associated with lower muscle strength, risk
of malnutrition and higher hsCRP, IL-6, IL-18, sTNFR2 level. Better
TUG and muscle strength performance were associated with higher
25OHD and lower PTH level. Only 6MWT and handgrip strength
were associated with muscle mass and TUG and muscle strength
were associated with lumbar spine Tscore.
Conclusions:
Poor physical performance is associated with
increased markers of inflammation. Impairment in gait related
activities was unrelated to muscle mass but were associated with
age, comorbidities, poor functional status and fat content, while
handgrip strength was associated mainly with appendicular muscle
mass and ACEI use.
P-227
Physical frailty predicts medical expenses in
community-dwelling, elderly patients: three-year prospective
findings from living profiles of older people surveys in Korea
J.H. Son
1
, S.Y. Kim
1
, C.W. Won
2
, H.R. Choi
1
, B.S. Kim
1
, M.S. Park
1
1
Kyung Hee University Medical Center, Seoul, Republic of Korea;
2
Republic of Korea
Objective:
With an aging population, medical expenses for elderly
patients are increasing rapidly. Frailty is currently considered an
important issue in geriatrics. The purpose of this study was to
investigate the effect of frailty on medical expenses in elderly
Korean patients.
Methods:
Data were gathered from the 2008 and 2011 Living
Profiles of Older People Surveys (from August 11, 2008 to February
20, 2012) and included 5,303 community-living Korean men and
women, aged 65 years or older. The five-item frailty index was
comprised of items on weight loss, exhaustion, weak grip strength,
slow walking speed, and low physical activity. Frailty data were
extracted from the 2008 Living Profiles of Older People Survey, and
out-of-pocket medical expenses data were extracted from the 2011
Living Profiles of Older People Survey. A generalized linear model
was used to analyze the correlation between frailty and medical
expenses after adjusting for sociodemographics, health behavior,
and health status factors.
Results:
Baseline frailty assessments grouped patients as robust
(43.3%), prefrail (49.3%), and frail (7.4%). After adjusting for
sociodemographics, health behavior, and health status variables,
frailty was found to increase outof-pocket medical expenses
(robust: ref., prefrail:
b
= 0.087 & P
<
0.001, frail:
b
= 0.143 &
P
<
0.001).
Conclusion:
Our findings suggested that frailty is an independent
predictor of increasing medical expenses in communitydwelling
elderly patients.
P-228
The effect of frailty on 3-year mortality in Korean
community-dwelling elderly
S.Y. Kim
1
, C.W. Won
1
, H.Y. Lee
1
1
Kyung Hee University Medical Center, Seoul, Republic of Korea
Objectives:
With the aging of population, incidence of frailty is
markedly increasing. But its association with mortality in Korean
elderly is lacking. The aim of this study is to examine the
association between frailty and mortality in Korean community-
dwelling elderly.
Methods:
Data were from the 2008 and 2011 Living Profiles of
Older People Survey (From August 11st 2008 to February 20th
2012) and included 4,014 men and women, aged 65 and older, living
in community in Korea. 5-item frailty index comprised of weight
loss, exhaustion, weak grip strength, slow walking speed, and low
physical activity. Participants with lack of data about frailty index
and people who were diagnosed with cancer, stroke, myocardial
infarction and angina were excluded. Mortality data were extracted
from 2011 Living Profiles of Older People Survey. Binomial logistic
regression models were constructed with frailty status regressed
on mortality, adjusting for variables.
Results:
Baseline frailty assessments yielded following results: non-
frail (39.74%), pre-frail (50.17%), frail (10.09%). Overall, 303 (7.55%)
participants died during the 3-year study period. After adjusting
for socio demographic variables, having a 2-year health check-
up or not, current smoker or not, BMI, GDS, taking enough
vegetables, fruits and milk products, and comorbid diseases
(tuberculosis, chronic renal failure, chronic bronchitis/emphysema),
frailty increased risk for mortality (HR = 1.675, 95% CI 1.040–2.697).
Conclusions:
In community-dwelling Korean elderly, those who
were frail and pre-frail elderly showed a higher risk of mortality
than the robust.
P-229
Older adults with sarcopenia versus age and sex-matched
controls: differences in physical and nutritional characteristics
S. Verlaan
1,2
, K. Brandt
3
, T. Hill
3
, J. McPhee
4
, S. Wijers
5
,
J. Hemsworth
5
, C. Seal
3
, The Provide E study group
1
Nutricia Research, Utrecht, Netherlands;
2
VU University Medical
Center, Amsterdam, Netherlands;
3
Newcastle University, Newcastle,
United Kingdom;
4
Manchester Metropolitan University, Manchester,
United Kingdom;
5
Nutricia Research, Nutricia Advanced Medical
Nutrition, Utrecht, Netherlands
Objectives:
Nutrition can influence the partly reversible process of
sarcopenia, which is a main cause of reduced physical mobility,
increased falls and fractures. Our goal was to compare physical and
nutritional status of sarcopenic non-protein-energy malnourished
older adults with the status of age-matched healthy older adults.