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Poster presentations / European Geriatric Medicine 6S1 (2015) S32

S156

S83

life situations and in geriatric care, their relatives, professional

caregivers and the health care stakeholders is mostly unknown.

Existing research data from a general population is not transferable

for an end-of-life care population. Therefore, an interprofessional

team of nursing scientists, psychologists, health economists and

physicians from different departments of university realize M-

EndoL, which aims to develop a patient- and family-centered

approach for handling MRSA/MRE in end-of-life care, taking into

account the complex situation of hospitalized patients and their

relatives.

Methods:

The study uses a mixed methods approach and

is conducted across two research phases and at two study

centers. In a first phase, patients and relatives are interviewed

using semi-structured questioning to explore information and

communication in clinical setting and the individual consequences

due to complaints, therapy and hygienic measures. Transcripts

are analyzed using principles of Grounded Theory and MAXQDA

software. In the second research phase, results are shared in focus

group discussions.

Results:

We will present first categorizations and hypothesis about

the impact of MRSA/MRE infection and colonization on geriatric

patients and their relatives.

Conclusions:

A synthesis of the research findings will result in a

best practice guide for handling MRSA/MRE in end-of-life care. The

guide will be developed using expert consensus.

The project is funded by Bundesministerium f ¨ur Bildung und

Forschung (BMBF). There are no conflicts of interest to be reported.

P-194

Terminal change in functional decline of nursing home

residents with and without advanced dementia

N. Theill

University of Zurich, Zurich, Switzerland

Background:

Decline in physical functioning has been reported to

indicate impending death of residents in long-term care. However,

the role of dementia remains unclear, as well as time of onset

of terminal decline and the amount of change compared to pre-

terminal decline.

Objectives:

To investigate terminal change in functional decline of

nursing home residents with advanced, mild or no dementia.

Methods:

Mulitphase growth models were applied to retrospective

data of the last 24 months of 44,811 deceased residents (mean age

at death: 87.46

±

7.17, 67.6% women) of 358 Swiss nursing homes

between 1998 and 2014. Physical functioning was assessed with

the activities of daily living (ADL) index of the Resident Assessment

Instrument-Minimum Data Set (RAI-MDS).

Results:

Results revealed an acceleration of functional decline

between two and three months before death in all three groups. For

individuals without dementia, terminal decline was 1.5 points per

month compared to 0.1 points during pre-terminal decline. While

residents with mild dementia only showed slight differences in

end-of-life trajectories compared to the non demented residents,

advanced dementia was related to a lower physical functioning as

well as less severe rate of terminal decline.

Conclusion:

Impending death of nursing home residents is

indicated by terminal change in functional decline between two

to three months before death. Although global level of physical

functioning is lowered in residents with advanced dementia, they

still show a considerable increase in end-of-life functional decline.

P-195

Treatment-related differences in health related quality of life

and disease specific symptoms among colon cancer survivors:

Results from the population-based PROFILES registry

S. Verhaar

1

, P. Vissers

2

, H. Maas

3

, L. van de Poll-Franse

2

, F. Erning

4

,

F. Mols

2

1

AIOS, Tilburg, Netherlands;

2

UVT, Tilburg, Netherlands;

3

Netherlands;

4

IKNL, Utrecht, Netherlands

Objectives:

The goal of this study was to compare health related

quality of life (HRQoL) and disease-specific symptoms between

colon cancer patients treated with surgery only (SU) and surgery

and adjuvant chemotherapy (SU+adjCT). Results were stratified for

those aged

<

70 and ≥70 years. HRQoL of patients was also compared

with an age- and sex-matched normative population.

Methods:

Patients diagnosed with colon cancer and surgically

treated between January 2000 and June 2009, as registered

within the population-based Eindhoven Cancer Registry, received

a questionnaire on HRQoL (EORTC QLQ-C30) and disease-

specific symptoms (EORTC QLQ-CR38) in 2010. EORTC QLC-C30

questionnaire was also completed by the normative population

(n = 685).

Results:

1606 (72%) colon cancer survivors responded to our

questionnaire. 854 colon cancer patients aged ≥70 were included in

this study, treated with SU (n = 643) or SU+adjCT (n = 211), with a

matched normative control group of 98. No statistically significant

differences on the scales of the EORTC QLQ-C30, both functioning

scales as subscales, were observed between colon cancer patients

treated with either SU or SU+adjCT and the normative population.

Conclusion:

No differences in HRQoL were found between colon

cancer patients aged ≥70, 1–10 years after diagnosis, treated with

either SU or SU+adjCT and a normative population aged ≥70. Long-

term HRQoL does not justify withholding adjuvant chemotherapy.

Furthermore, HRQoL-measurements in an elderly population may

be complex and actual HRQoL instruments may lack the ability to

discriminate HRQoL in elderly patients.

P-196

Dementia Village Singapore: visions of the future

X.Y. Yap

1

, M.Y. Yap

2

1

Changi General Hospital, Singapore, Singapore;

2

Changi General

Hospital, Singapore

Introduction:

In place of traditional nursing homes, the

Netherlands has pioneered the first dementia village in the world,

the De Hogeweyk. We imagine how a similar-styled village can be

built in Singapore, and its feasibility.

The Dementia Village:

Land scarce Singapore would be the perfect

setting for a block of condominium-style apartments. It will be

situated within a gated premise with security cameras, replete

with pavements, cycling paths and gardens. Residents will be given

the independence to walk around as they please.

The village will be helmed by a myriad of healthcare staff who will

“live” in the same community. They will patrol the village in their

own clothes and look after the villagers in a discreet manner.

The village will be self-equipped with its own facilities. There will

be a grocery store, hair salon, restaurant, chapel and a GP clinic.

There will also be a town hall, where villagers can mingle and have

classes such as cooking and art therapy.

It is hoped that the village will create a safe environment for

dementia patients to live as normal a life as they could, in a

dignified manner.

Limitations:

The cost of building and maintaining the compounds

will be the main consideration, as well as manpower recruitment

and training. Also criteria have to be put in place to achieve a deft

balance between demand and supply.