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Poster presentations / European Geriatric Medicine 6S1 (2015) S32

S156

S85

abductors, hip extensors, elbow extensors and elbow flexors). The

Pearson’s correlation test was used to test the relationship between

lean mass and muscle strength.

Results:

The mean values were 9.1

±

10.1 kg/m

2

for ALM/ht

2

,

15.9

±

6.9 kg for grip strength, and for isometric strength they

ranged from 56.9

±

31.5N (elbow extensors) to 101.3

±

58.2N (knee

extensors). Correlation between ALM/ht

2

and grip strength was

significant (r = 0.28; p = 0.014) as well as between ALM/ht

2

and

strength of all muscle groups except for hip abductors and

extensors. The correlations ranged from 0.38 (elbow extensors and

ankle extensors) to 0.52 (elbow extensors). Correlation between

lean mass of the dominant leg and grip strength, was also significant

(r = 0.44; p = 0.001) whereas the relation between lean mass of

the dominant arm and grip strength was not significant (r = 0.19;

p = 0.66).

Conclusion:

There seems to be a positive correlation between

appendicular lean mass and strength of various muscle groups

including grip strength in nursing home residents. Longitudinal

studies are needed to better understand the clinical impact of this

observation.

P-201

Impact of the frailty status on muscle mass and muscle

strength of nursing home residents

F. Buckinx

1

, J.-L. Croisier

1

, J.-Y. Reginster

1

, J. Petermans

1

,

O. Bruy `ere

1

1

University of Li`ege, Li`ege, Belgium

Background:

The aim of this study was to compare muscle mass

and muscle strength of frail, pre-frail and robust subjects living in

nursing homes.

Methods:

This is a cross sectional study performed in 10 nursing

homes in Li `ege, Belgium. Patients were classified as frail, pre-frail

or robust according to Fried’s definition. Muscle mass, and more

specifically appendicular lean mass divided by height squared,

was assessed using a recently validated bioelectrical impedance

analyzer, the InBody S10 (Buckinx et al. 2015). Grip strength was

assessed with a hydraulic dynamometer and maximal isometric

strength of 8 different muscle groups (i.e. knee extensors, knee

flexors, ankle extensors, ankle flexors, hip abductors, hip extensors,

elbow flexors and elbow extensors) was assessed with a microFET2

hand-held dynamometer.

Results:

A total of 250 subjects were included in this study

(81.2

±

10.3 years, 67.2% of women). After adjustment for age, sex

and BMI, muscle strength at all sites was significantly different

between robust, pre-frail and frail groups. However, the difference

in appendicular lean mass was not significant between the three

groups based on the frailty status.

Conclusion:

Frailty status, among nursing home residents, seems

to be associated with reduction in muscle strength but not with

muscle mass.

P-202

Drugs, frailty and falls. The Toledo Study for Healthy Aging

M. ´A. Caballero Mora

1

, M. Vald ´es-Aragon ´es

2

, F.J. Manzano Lista

3

,

C. Alonso Bouzon

4

, R. Petidier Torregrossa

4

1

Hospital Universitario de Getafe, Getafe, Madrid, Spain;

2

Hospital

Universitario de Getafe, Madrid, Spain;

3

Hospital Virgen del Valle,

Toledo, Spain;

4

Hospital Universitario de Getafe, Getafe, Spain

Objectives:

Interventions to avoid risk factors associated with

frailty are needed among others reduction of drugs to prevent

falls. However do not exist studies that analyze the relationship

between frailty and drugs. Our objective is to evaluate association

between number of drugs and frailty with recurrent falls (RF) in

the elderly.

Methods:

1723 subjects from the Toledo Study for Healthy Aging,

a prospective Spanish cohort study. RF was defined as two or more

falls in the last year. Frailty was assessed with three different scales:

the Fried’s scale, the Frailty Index and the Frailty Trait Scale. And

finally, the number of drugs was defined as the number of drug

being taken when the interview was done.

Logistic regression models were used to assess this relationship

using BMI, age and sex as possible confounders.

Results:

Independently whether the frailty scale is included into

the model and the scale used, the number of drugs was associated

with RF, OR (95% CI) for an increment of one drug range from

1.085 (1.014–1.160) to 1.087 (1.016–1.163). If we change the order of

inclusion in the statistical model, we observed the same effect with

the frailty score, OR (95% CI) were 3.800 (2.097–6.901), 1.031(1.015–

1.047) and 1.032 (1.013–1.052) for Frail vs Robust (Fried’s scale) and

for an increment of 1 point in the FTS and FI score, respectively.

Conclusions:

Independently of the frailty scale used, the number

of drugs and frailty are two independent risk factors of recurrent

falls.

P-203

Sarcopenia in elder population with good functional

capabilities

Evaluation of functionality and detection

J.J. Calvo Aguirre

1

, O. Bueno Ya˜nez

2

, A. Araneta Herguedas

1

,

J. Zubeldia Etxeberria

1

, N. Zinkunegi Zubizarreta

1

, M. Ugartemendia

Yerobi

1

1

SESOSGI, San Sebastian, Spain;

2

Geriatric Nursing. Residencia Sagrado

Coraz´on, Paseo Gabierrota, Spain

Objectives:

The active ageing (WHO) pretends to optimize the

health opportunities to improve the elderly population’s life quality.

The evaluation of the functional capacity in an elderly population

with a good level of basal functionality, allows to detect risk

situations and subsidiary sarcopenia improvement, by means of

an intervention program.

Method:

137 persons were evaluated, all of them with a

good level of functionality and autonomous mobility. 103 lived

in their community and 34 in residences. Initial evaluation

included measurement of anthropometric parameters, history

of falls, nutritional and clinic status, polipharmacy, functional

status, life quality, MARCHA DUAL, functional status according to

Short Physical Performance Battery (SPPB), walking speed, dual

walk, muscular strength measured by dynamometry and muscle

mass measured by impedanciometry. Sarcopenia diagnosis criteria

were established by meeting EWGSOP and Janssen & Masanes

criteria. Physical performance status was evaluated by crossed-

press strength tests, walking speed and muscle mass index.

Results:

The average age of the population is 76.6 years (74.6 in the

community and 84.3 in the residence). The residential population

presents functional tests below the communal. In the communal

population, exist 5% of presarcopenia cases and 6% of sarcopenia.

In the residential, exist 24% of people with sarcopenia. A physical

exercise program is designed for the total population.

Conclusions:

Sarcopenia is more frequent in the residential environment than

in the communal.

A multicomponent physical exercise program is presented.

P-204

The FNIH-criteria for sarcopenia predict 12 year mortality

in ambulatory older men

S. De Buyser

1

, M. Petrovic

2

, Y. Taes

1

, B. Lapauw

1

, K. Toye

1

,

J.-M. Kaufman

1

, S. Goemaere

1

1

Ghent University, Ghent, Belgium;

2

Dept. of Geriatrics, Ghent

University Hospital, Ghent, Belgium

Objectives:

The Foundation for the National Institutes of Health

[FNIH] Sarcopenia Project recently developed new criteria for

diagnosis of weakness and low muscle mass in older adults.

These criteria were associated with increased likelihood for