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Late-breaking abstracts / European Geriatric Medicine 6S1 (2015) S177

S187

S181

population and the impact transfusion requirement had on day one

mobilisation.

Method:

A retrospective study using data collated for National

Hip Fracture database for period August-December 2014. Data was

inclusive of anticoagulation.

Results:

115 patients were in the study with age range of 60–

100, with a female predominance (female 84: male 31). 31

patients required blood transfusions (27%) and 10% requiring

transfusion were anticoagulated. Age, gender, and ASA grade were

not statistically significant risk factors. Fracture type (p value

0.019), operation type (

<

0.001), and pre-operative haemoglobin

(0.015) were statistically significant. Intertrochanteric (42%), and

intracapsular displaced (35%) fractures were associated with higher

rates of postoperative transfusion. Fixation with Sliding Hip

Screws (SHS) accounted for 48 % of post-operative transfusions

whilst Intramedullary (IM) Nail accounted for 16%. Pre-operative

haemoglobin

<

110 was associated with requiring transfusion

(haemoglobin; 80–89 (100% transfusion rate), 90–98(83%), and

100–110 (77%)).

63% patients not receiving, compared with 74% of patients receiving

transfusion mobilised day one post-operatively.

Conclusion:

We identified similar risk factors as previous

studies and this will guide our pre-operative and post-operative

management. This study identified SHS rather than IM nail

requiring post-operative transfusion at higher rates. This finding

may be due to a combination of population size in study as well as

operation preference (IM nail fixation-13% of total surgeries, SHS-

34%)

P-467

Is frailty a prognostic factor for critically ill elderly patients?

M.C. Kizilarslanoglu

1,2

, R. Civelek

2

, M.K. Kilic

2

, F. Sumer

2

,

H.D. Varan

2

, O. Kara

2

, G. Arik

2

, M. Turkoglu

2

, G. Aygencel

2

,

Z. Ulger

2

1

Hacettepe University School of Medicine, Ankara, Turkey;

2

Gazi

University School of Medicine, Ankara, Turkey

Objective:

It was aimed to investigate the effects of frailty on

clinical outcomes of the patients staying intensive care unit (ICU).

Methods:

In this prospective study, 122 patients (59 frail, 37 pre-

frail and 26 robust) were included. A frailty index (FI) (Krishnan

et al. Age Ageing 2014) derived from comprehensive geriatric

assessment parameters was used for the evaluation. The FI score of

≤0.25 was considered as robust, 0.25–0.40 as pre-frail and

>

0.40 as

frail. The prognostic effects of FI were investigated and also, FI and

APACHE II and SOFA scores, the prognostic scores using in ICU, were

compared.

Results:

Median age of the patients was 71 years-old (min-max: 60–

101) and 50.8% was male. Mortality rate and median length of stay

(LOS) of the patients in the ICU were 51.6% and 8 days (min-max:

1–148), respectively. Mortality rate in the hospital was significantly

higher in the frail group compared to pre-frail and robust groups

(73.1%, 62.2% and 45.8%, respectively, p = 0.046). Mortality rate in

ICU was also higher in the frail group compared to pre-frail and

robust groups (69.2%, 56.8% and 40.7%, respectively, p = 0.040). In

multivariate analysis, it was found that LOS in ICU (OR: 1.067, 95%CI:

1.021–1.114), SOFA score (OR: 1.272, 95%CI: 1.096–1.476) and FI (OR:

39.019, 95%CI: 1.235–1232.537) were the independent correlates

for the ICU mortality (p = 0.004, p = 0.002 and 0.038, respectively).

There was weak but statistically significant positive correlations

between APACHE II and FI scores (r = 0.190, p = 0.036).

Conclusions:

As a conclusion, FI may be used as a predictor for the

evaluation of elderly patients’ clinical outcomes in ICUs.

P-468

The association of sarcopenia with depression and functional

status among elderly persons

A. Kılavuz

1

, R. Meseri

2

, S. Savas

3

, H. Simsek

4

, S. Sahin

5

, D. Hopanci

Bicakli

6

, F. Sarac

7

, M. Uyar

8

, F. Akcicek

7

1

Ege University Medical Faculty, Internal Medicine Department, Izmir,

Turkey;

2

Ege University,Izmir Ataturk School Of Health, Nutrition

And Dietetics Section, Izmir, Turkey;

3

Ege University Medical Faculty,

Internal Medicine Department, Geriatrics Section, Izmir, Turkey;

4

9 Eylul University Medical Faculty, Depertment of Public Health,

Izmir, Turkey;

5

Ege University Medical Faculty, Department of

Geriatric Medicine, Izmir, Turkey;

6

Ege University Medical Faculty,

Department of Medical Oncology, Izmir, Turkey;

7

Ege University

Medical Faculty, Izmir, Turkey;

8

Ege University Medical Faculty,

Department of Anaesthesiology and Reanimation, Izmir, Turkey

Objective:

Association of depressive symptoms and activities of

daily living (ADL) and lower hand-grip strength (HGS) in older

persons has been reported. Our aim is to evaluate the association of

sarcopenia with functional status and depressive symptoms among

elderly persons aged 65 years and older living at their homes in

˙Izmir, Turkey.

Methods and Subjects:

Community dwelling 861 ≥65 years old

ambulatory people living in Bornova region in the center of Izmir

were taken into the study which were selected from ‘prevalence

and risk factors of sarcopenia study’ in the same district. For

diagnosis of sarcopenia The European Working Group on Sarcopenia

in Older People criteria were adopted. Geriatric Depression Scale-

Short Form, ADL, The Lawton Brody Instrumental ADL (IADL) scale,

calf circumference (CC), HGS, 6-m GS were applied. RESULTS: Mean

age of 861 people was 72.2

±

5.8 years (58.9% females). Sarcopenia

was identified in 40 elderly (4.64%). People with sarcopenia showed

a statistically significant lower IADL score, CC, HGS, GS, BMI and

statistically significant higher age. After adjusting for potential

confounders, an increased risk of sarcopenia was found for age

groups 75–84 (OR 4.4; 95% CI 1.4–14.3) and 85 and over (OR 9.1;

95% CI 1.5–52.9) and in those with low BMI (

<

22 kg/m

2

) (OR 21.6;

95% CI 6.8–68.2).

Conclusion:

Only IADL was associated with increased sarcopenia

risk in ambulatory community dwelling elderly people. However

ADL and depressive symptoms were not associated with increased

sarcopenia risk.

P-469

Alzheimer and dementia: when the adult grandchildren

become the primary caregivers of their grandparents

. . .

D. Huvent-Grelle

1

, I. Delabriere

1

, J.B. Beuscart

1

, L. Delannoy

1

,

M. Manechez

1

, F. Puisieux

1

, E. Boulanger

2

1

CHRU Lille, Lille, France;

2

Lille 2 University, Lille cedex, France

Background:

Alzheimer’s disease and other vascular cognitive

disorders are common disturbances in the elderly. Dementia often

has a serious impact on family life. Most demented patients are

cared for at home by family members, usually elderly spouses.

Adult grandchildren (AGC) are also a significant contingent of elder

care providers. The number of AGC as caregivers is likely to increase

because demented cases are expected to double by 2030 and triple

by 2050.

Methods:

The participants (dyad: demented grandparent (GP)

and AGC) have been recruited through the system of the French

National Alzheimer Data Base. A structured telephone non recorded

interview lasting about 15 minutes was conducted with the AGC.

They were asked what type of caregiving activities they provide

for their GP and if they encountered physical or mental health

problems associated with their caregiving experience.

Results:

The sample group had 70 aged demented GP and 70 AGC. A

vast majority of the AGC were women, mean age 38 years, married,

employed. They had two children on average. The demented GP