European Geriatric Medicine - Supplement 1 - Volume 6

European Geriatric Medicine 6S1 (2015) S177–S187

Available

online

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Late-breaking abstracts

Oral presentations

O-091

Cut-off points for muscle mass, not for grip strength or gait

speed, determine variability in the prevalence of sarcopenia

F. Masan ´es

, X. Rojano

, A. Salv `a

, J.A. Serra-Rexach

, I. Artaza

F. Formiga

, F. Cuesta

, A. L ´opez Soto

, D. Ru´ız

, A.J. Cruz-Jentoft

Hospital Cl´ınic de Barcelona, Barcelona, Spain;

Fundaci´o Salut

i Envelliment, Barcelona, Spain;

Hospital General Universitario

Gregorio Mara˜n´on, Madrid, Spain;

Igurco Servicios Sociosanitarios,

Erandio-Bizkaia, Spain;

Hospital Universitari de Bellvitge, L’Hospitalet

de Llobregat, Spain;

Hospital Cl´ınico San Carlos, Madrid, Spain;

Hospital de Sant Pau, Barcelona, Spain;

Hospital Universitario

Ram´on y Cajal, Madrid, Spain

Background:

The EWGSOP criteria proposed different methods and

cut-off points for each of the three parameters included in the

definition of sarcopenia (muscle mass, muscle strength, physical

performance). This facilitates the implementation in the clinical

practice, but limits comparability between studies and leads to wide

differences in published prevalences of sarcopenia. The aim of this

study was to assess how changes in cut-off points for muscle mass,

gait speed and grip strength affects the prevalence of sarcopenia

according to the EWGSOP criteria.

Methods:

Cross sectional analysis of 298 older individuals from

outpatient clinics and 276 from nursing homes. We measured

muscle mass through bioimpedance, grip strength and gait speed

and assessed how changes in cut-offs changed the prevalence of

sarcopenia in both sets.

Results:

For MMI in women a rise from 5.45 to 6.68 kg/m

increased

sarco-penia from 4% to 23% in outpatient clinics and from 9% to 47%

in nursing homes. In men a rise from 7.25 to 8.87 kg/m

increased

sarcopenia from 1% to 22% in outpatient clinics and from 6% to 41%

in nursing homes. Changes in speed and strength had limited effect

in the prevalence of sarcopenia.

Conclusion:

Muscle mass cut-off points are the most important

parameter that influences the prevalence of sarcopenia in these

populations. Changes in cut-off points for gait speed and grip

strength had a limited impact.

O-092

Blood pressure and dementia: The HUNT-HMS Study

J. Gabin

, K. Tambs

2,3

, I. Saltvedt

2,3

, E. Sund

, J. Holmen

NTNU, Trondheim, Norway;

St. Olav University Hospital, Trondheim,

Norway;

Norwegian University of Science and Technology (NTNU),

Trondheim, Norway;

Researcher, HUNT Research Centre, Levanger,

Norway;

HUNT Research Centre, Department of Public Health and

General Practice, Norwegian University of Science and Technology

(NTNU), Levanger, Norway

Objectives:

Blood pressure has been a subject of interest in the

epidemiology of dementia due to observations that vascular factors

may be associated with Alzheimer disease and vascular dementia.

However, results regarding blood pressure remain inconclusive.

The focus of this article is on the association between dementia

and blood pressure on a prospective case-cohort study population-

based sample.

Methods:

Utilizing data obtained during the period of 1995–2011,

983 participants of the HUNT-HMS study were diagnosed with

Alzheimer disease, mixed dementia or vascular dementia. Dementia

subjects were 67 percent female, had an average age of 60, and a

blood pressure average of 143 systolic over 87 diastolic during their

participation in the first HUNT study that occurred in 1984–1986.

Incident dementia was ascertained in individuals up to 27 years

thereafter and multiple logistic regression analyses were conducted

examining the association between blood pressure and AD, mixed

AD or VaD.

Results:

Data was nonlinear and an interaction with age and systolic

blood pressure occurred around 60–65 years of age. No association

with blood pressure and dementia in samples under the age of 65.

Over the age of 65, inverse associations between systolic blood

pressure and AD were observed. Adverse associations between

systolic and diastolic blood pressure and VaD were also observed.

Conclusions:

We question whether inverse associations between

systolic blood pressure and dementia can be due to a survival bias.

O-093

Prevalence, mortality and readmission of people with

dementia, delirium and other cognitive spectrum disorders

in the general hospital

E. Reynish

University of Stirling, Stirling, United Kingdom

Objective:

To understand the outcomes of cognitive spectrum

disorders in the general hospital.

Methods:

Study design:

Cross sectional study examining routine

hospital data from all acute medical hospital admissions aged 65

years and over.

Setting:

NHS Fife, Scotland, UK 2012.

Participants:

All patients aged 65 years or older underwent the Older Persons

Routine Acute Assessment (OPRAA) within the first 24hrs of

admission.

Variables:

Variables accessed via OPRAA include: Abbreviated

Mental test (AMT), Confusion Assessment Method (CAM), Clinical

assessment of delirium undertaken by trained specialist nurses,

Documentation of the presence of a pre-admission diagnosis of

dementia, and Katz Activities of daily living scale. The OPRAA

dataset is linked to the Scottish Morbidity Records 01 (SMR01), the

General Register Office (GRO), and the master Community Health

Index (CHI).

Statistical methods:

Prevalence rates for all cognitive spectrum

disorders were calculated. Outcomes of mortality and readmission

were calculated for patients with and without cognitive spectrum

disorders. The

test was used for comparison of outcomes

between those with and without cognitive impairment.

Results:

Participants:

In total 9133 admissions were recorded for in-

dividuals aged 65 years and over for the time period Jan–Dec 2012.

Main results:

The prevalence of any cognitive spectrum disorder in

emergency admissions aged 65 years and over was 34.5% (95%

CI 33.4–35.6). Twenty three point five percent 23.5% (95% CI