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Poster presentations / European Geriatric Medicine 6S1 (2015) S32

S156

S71

VHD patients undergone valve replacement surgery before and after

HVC implementation were analysed.

Results:

Twenty-height older VHD patients admitted to the HVC

between April 2014 and February 2015 underwent cardiac surgery.

HVC patients were older relative to those treated in 2013 (n = 121)

(79.1

±

4.3 vs. 76.5

±

4.2 years; p

<

0.01), with no differences in gender

distribution, VHD type and severity, NYHA class or number of co-

morbid conditions. The total length of hospital stay was unvaried,

despite longer time spent in postoperative intensive care unit

by HVC patients (159.4

±

166.7 vs. 86.0

±

70.0 hours; p

<

0.001).

The number of specialist consultations was reduced after HVC

implementation (0.8

±

1.0 vs. 2.5

±

1.9; p

<

0.0001). None of HVC

patients died during hospitalisation, whereas 4 patients died in

2013 (p = 0.7).

Conclusion:

The implementation of a multidisciplinary clinical

pathway dedicated to geriatric patients with VHD allows extending

eligibility to surgery to older and frailer subjects and optimising

the use of resources, without impacting mortality or length of

hospitalisation.

P-147

The relationship between oncological (ECOG PS), geriatric

[Comprehensive Geriatric Assessment (CGA), and Rockwood

Frailty Index (IF)] evaluation: preliminary results in a cohort

of oncogeriatric patients

F. Monacelli

University of Genoa, Genoa, Italy

Objective:

CGA is the gold standard for elderly assessment to

optimize cancer treatment and to stratify their biological condition

(frail, pre-frail, fit). However, the method is time-consuming and of

specialist expertise. Other tools did not provide the same specificity.

We plan to compare different evaluation scales to assess the best

predicting oncogeriatric tool.

Methods:

First visit included ECOG PS, CGA, IF, Short Form Health

Survey-36 (QoL). Patients were assessed after 1 month for mortality,

3/6 and 12 months for QoL, functional status, performance status

and overall mortality.

Results:

Fifty-two patients (29 females, 23 males), with solid

tumour, mean age of 79

±

1.0 years were enrolled from January

2015 in an Italian hospital. Respectively, 10% of pt by ECOG PS,

and 35% of pt by CGA were frail. By IF, 28 pts were frail (55%), 23

pre-frail (45%) and 1 was fit. The correlation between the last two

tools was moderate (R=+0.60, p

<

0.001).

CGA unmasked several clinical problems: delirium (8%), depression

(35%), insomnia (4%), pain (33%), malnutrition (35%), lack of

social support (6%), cognitive deficit (14%), osteoporosis (10%),

rehabilitation need (15%),others (8%).

The overall mortality was of 7% (4/52 patients). The 30-day

mortality after surgery was of 14% (3/21 pts) with 3 patients

assessed as frail by both CGA and IF and one patient assessed

as fit by CGA and pre frail by IF.

Conclusions:

The preliminary comparison between CGA and IF

showed different predicitivity. The larger enrolment and follow

up will contribute to identify the best predicting tool in

oncogeriatrics.

P-148

Transcatheter aortic valve implantation may modify the

expected risk of mortality according to the Multidimensional

Prognosis Index

M. Paccalin

University Hospital, Poitiers, France

Objective:

To assess the impact of transcatheter aortic valve

implantation (TAVI) on expected prognosis according to the frailty

status.

Participants:

Consecutive patients who underwent TAVI and

a complete comprehensive geriatric assessment (CGA) between

January 2013 and September 2014.

Measurements:

Baseline Demographic data and a cardiologic

evaluation were recorded. The CGA included information on

functional, cognitive and nutritional status; risk of pressure sore;

comorbidities; medications; and social support network; the

information was used to calculate the multidimensional prognostic

index (MPI) for mortality using a previously validated algorithm.

The final MPI score is divided into three levels of mortality risk:

MPI-1, low risk (MPI ≤0.33), MPI-2, moderate risk (from 0.34–

0.66); and MPI-3, high risk (MPI ≥0.66).The vital status was

assessed in March 2015 through visits or phone calls to the general

practitioners.

Results:

50 patients were enrolled; mean age: 86.5

±

4.2 years

and mean European system for cardiac operative risk evaluation

(EuroSCORE): 18.35

±

11.58. Thirty patients (60%) were in the MPI-1

group, 19 (38%) in the MPI-2 group and 1 patient in the MPI-3 group.

The rate of mortality was 26% 1 year after TAVI. No association

between EuroSCORE, age or MPI-score was found (p = 0.19; p = 0.52

and p = 0.51 respectively).

Conclusion:

In this study including very old patients, frailty was

not associated significantly with increased mortality after TAVI.

However, the results showed the effectiveness of this innovative

procedure that may decrease the expected mortality between the

most frail and the least frail according to the MPI.

P-149

Are all the former Siberian deportees with posttraumatic stress

disorder patients at risk?

A. Parnicka

1

, K. Piotrowicz

2

, M. Mielima˛ka

3

, K. Basista

1

,

J. Walczewska

1

, A. Skalska

2

, K. Rutkowski

3

, T. Grodzicki

2

1

Department of Internal Medicine and Gerontology, Jagiellonian

University Medical College, Krak´ow, Poland;

2

Poland;

3

Jagiellonian

University Medical College, Krak´ow, Poland

Objective:

The primary aim of the analysis was to assess the group

of elderly people suffering from the post traumatic stress disorder

(PTSD) with the Identification of Seniors at Risk (ISAR) tool. The

secondary aims were to test the relationships between ISAR and the

Canadian Study of Health and Aging Clinical Frailty Scale (CSHA-

CFS), muscle strength, and mobility according to the Timed Up and

Go (TUG) test.

Methods:

The group consisted of the outpatients aged ≥60 years

who had been deported during World War II or born in exile in

the Soviet Union. PTSD was diagnosed according to criteria of the

DSM-IV. Additionally, ISAR tool and the CSHA Clinical Frailty Scale

were used, and the muscle strength and mobility were measured.

Results:

The mean(

±

SD) age of 68 patients:70.4

±

6.8 years (min.-

max.:60–88 years); 55.9% men. ISAR (median; Q1, Q3): 3.5 (2, 5)

points; with higher results for women [4 (3, 5) vs 3 (2, 4) for

men;p = 0.02]. At risk was 85.3% and 70.6% of the group, according

to the threshold of two and three points, respectively. The

three most common complaints: sight problems (77.9%), using

>

3 medications/day (76.5%) and serious memory problems (52.9%).

There were significant correlations between ISAR and CSHA-CFS

(r = 0.718, p

<

0.001), and muscle strength (r = −0.433, p

<

0.001), and

the results of TUG (r = 0.415, p

<

0.001), respectively.

Conclusions:

The application of ISAR tool revealed that most of the

elderly patients with PTSD were vulnerable and at risk for future

adverse outcomes. ISAR correlated well with the CSHA Clinical

Frailty Scale as well as with the muscle strength and mobility.