European Geriatric Medicine - Supplement 1 - Volume 6 - September 2015

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Poster presentations / European Geriatric Medicine 6S1 (2015) S32–S156 S59
toxin positive, in 24 patients (9.3%) was antigen positive and
toxin negative. Ciprofloxacin was still the most used antibiotic in
departments of previous hospitalisation and our’s too. Only 48%
patients with diarrhea used probiotics during hospitalization on
previous departments, but up to 95% on our. We analysed several
other risk factors.
The most used antibiotics didn’t change over the years. The
occurrence of CE with positivity of toxin seems to decrease
from 10.2% to 8.5% (not statistically significant, p = 0.554), this
slight decrease encourages us to stay vigilant. Further changes in
rational antibiotic prescription, use of probiotics and strict hygienic
measures have to be done consistently.
P-100
Special features of deep venous thrombosis complicated
pulmonary embolism topics in the elderly
M. Lamloum1, M. Boudokhane1 , M. Ben Nasr1 , F. Said1 ,
A. Hamzaoui1 , T. Ben Salem1 , I. Ben Ghorbel1, M. Khanfir1,
M.H. Houman1
1La Rabta Hospital, Tunis, Tunisia
Introduction: Deep vein thrombosis (DVT) is a frequent clinical
situation at the origin of morbidity and mortality still too high.
Since it may be complicated by pulmonary embolism can be life-
threatening.
Our goal is to study the clinical, paraclinical and complicated
evolutionary characteristics PST pulmonary embolism (DVT/PE) in
the elderly.
Materials: We performed a retrospective descriptive study of
patient records hospitalized for DVT/PE over a period of 18 years.
We compared patients with a DVT/PE (G1) versus those who had
not had pulmonary embolism complicating PST (G2).
Results: We collected 424 cases of DVT. The DVT/PE (G1) were
observed in 101 patients. They were 51 women and 50 men.
Uncomplicated DVT pulmonary embolism (G2) were observed in
323 patients. They were 200 women and 123 men. On thrombotic
risk factors, there was no significant difference between the 2
groups. The frequency of recurrence were similar between the 2
groups. There was also no significant etiological difference between
the 2 groups. Indeed, neoplasia was observed in 15patients G1 and
62 patients in G2 (p = 0.9). Thrombophilia, Beh ¸cet’s disease and
hyperhomocysteinemia was observed respectively in 2, 3 and 8
patients in group G1 versus 6, 4 and 13 patients in G2. The
idiopathic DVT in 38 patients remained in G1 and 86 patients
in G2 (p = 0.6).
Conclusion: Pulmonary embolism is a common and serious
complication of DVT hence the interest to know well the risk factors
predisposing to this complication
P-101
The etiologies of deep venous thrombosis in the elderly
M. Lamloum1, M. Ben Nasr1, M. Boudokhane1 , F. Said1 ,
A. Hamzaoui1 , T. Ben Salem1 , I. Ben Ghorbel1, M. Khanfir1,
M.H. Houman1
1La Rabta Hospital, Tunis, Tunisia
Introduction: Deep vein thrombosis is common clinical situation
requiring etiological investigation because it may be the first
manifestation of an underlying disease. Indeed, thromboembolic
disease is multifactorial and multigenic, the etiological investigation
differs depending on the age and ground.
Materials and Methods: We performed a retrospective, descriptive
and analytical in a series of 424 cases of venous thrombosis,
conducted internal medicine department of the University Hospital
Rabta Tunis over 18 years (1997–2015). The objective of our study is
to investigate the different etiologies of venous thromboembolism
in the elderly.
Results: It was 424 patients, mean age 65.5 years including
223 women and 201 men. All patients were hospitalized for
etiological investigation with an average stay of 10, 31 days and
an etiological diagnosis time of 6.125 months. The main risk factors
for thromboembolism in the elderly were smoking and bed rest in
respectively 32.85% and 29.78%. The DVT was paraneoplastic in 77
cases of which 66 were revealing. The hyperhomocysteinemia was
responsible for deep vein thrombosis in 4.95%. Among our patients,
seven had a Behcet’s disease and eight had thrombophilia. The DVT
remains undetermined etiology in 29.24%.
Conclusion: The variety of etiologies it difficult diagnostic
algorithm. Nevertheless, apart from the obvious iatrogenic causes
a complementary examination must be performed as venous
thrombosis are in most cases revealing underlying neoplasia.
P-102
Osteoarticular manifestation of Horton Disease (Giant-cell
arteritis, GCA): report of 47 cases
M. Lamloum1, W. Ben Salem1, M. Ben1 , A. Hamzaoui1, F. Said1,
T. Ben Salem1 , I. Ben Ghorbel1, M. Khanfir1, M.H. Houman1
1La Rabta Hospital, Tunis, Tunisia
Introduction: Horton disease is granulomatouse panrarteritis. The
common rheumatic manifestation is polymyalgia rheumatic (PMR)
observed in 47% of cases. The other joint manifestations are less
common
Our study was aimed at determining, clinical, therapeutic profile of
osteoarticular manifestation during Horton disease
Patients: A retrospective study of the all cases of Horton disease
during a period 20 years. Horton’s disease diagnosed according to
American College of Rheumatology criteria.
Results: 80 Cases with a Horton disease were observed, these were
38 males and 42 females with mean age of 70 years. Osteoarticular
manifestations were seen in 47 of patients, including 23 females
and 24 males. They inaugurated the clinical picture in 26 cases.
The circumstances of exploration were headache in 75 cases, ocular
signs in 30 cases, general signs in 19 cases. Typical medical picture
of polymialgia rheumatica was presented in 35 of cases, 4 of them
were presented with isolated involvement of shoulder girdle. PMR
presented with the focal neurologic signs in 18 cases. Neck pain
was observed in 38 of cases, and myalgia in 15 of cases.
Temporal artery biopsy was done for all of the patients. It was
positive in 38 patients.
Biologic inflammatory syndrome was seen in 58 cases.
Corticosteroids were prescribed at the dose of 0.5 to 1mg / kg / day.
methotrexate has been used in combination with corticosteroids in
19 patients.
The evolution of the osteoarticular manifestations in Horton disease
was marked by the disappearance of clinical signs with mean period
of 22 days.
P-103
Giant cell arteritis in Tunisia: demographic, clinical and
laboratory characteristics: analysis of 90 patients
M. Lamloum1, T. Ben Salem1, T. Molka 1, W. Ben Salem1, F. Said1 ,
A. Hamzaoui1, J. Bellagha 1, I. Ben Ghorbel 1, M. Khanfir1,
M.H. Houman1
1La Rabta Hospital, Tunis, Tunisia
Purpose: Giant-cell arteritis is an immune-mediated diesease
characterized by granulomatous infiltrates in the wal of m´edium-
size and large arteritis To study the demographic,clinical and
laboratory characteristics of temporal arteritis Tunisian patients,
we performed a retrospective review of all cases diagnosed as
temporal arteritis in in a department of internal Medecine in over
a 30-years (1986–2015). All patients fulfilled the criteria of the
American College of Rhumatology.