European Geriatric Medicine - Supplement 1 - Volume 6

Oral presentations / European Geriatric Medicine 6S1 (2015) S5

–

S31

S27

There were 13872 patients eligible for analysis, 9998 subjects aged

65 to 79 and 3874 80 years old and over. Older patients were

significantly more female (47.3%, p

0.0001), more underweight

(3.5% vs. 2.4%, p

0.001) and more hypoalbuminemic (serum

albumin

35 g/L, p

0.002). Importantly, subjects aged 80 years and

older had significantly more comorbidities (55.8%

4 concomitant

diseases), in particular heart failure (p

0.0001), cardiovascular

disease (p

0.0001), cancers (p

0.004), and cerebrovascular

episodes (p

0.0001). Prevalence of renal anemia (i.e. Hb

10 g/dl)

despite treatment was not significantly different among groups.

Older subjects on dialysis are an extremely vulnerable population.

Therapeutic concepts are currently focused predominantly on

nephrologic issues and should be expanded to cover geriatric

syndromes and rehabilitative approaches.

O-076

Health related quality of life (HRQOL) in older patients waiting

for kidney transplantation in Norway

K. Lønning

, T. Bernklev

, K. Midtvedt

, M. Andersen

, K. Heldal

Oslo University Hospital, Rikshospitalet, Oslo, Norway;

Research

Unit, Telemark Hospital HF and Institute of Clinical Medicine,

University of Oslo, SKIEN, Norway;

Oslo University Hospital HF, Oslo,

Norway;

Oslo University Hospital HF and University of Oslo, Oslo,

Norway;

Telemark Hospital HF and University of Oslo, SKIEN, Norway

Introduction:

Both incidence and age of patients developing

end stage renal disease (ESRD) are increasing. Consequently, an

increasing number of older patients become potential candidates

for kidney transplantation (KTx). While waiting for KTx the patients

carry the burden of ESRD and are often in need of dialysis. This

affects HRQOL. There is a lack of studies measuring HRQOL in older

recipients enlisted for KTx. The aim of this study is to measure

changes in HRQOL longitudinally in patients

65 years of age, from

time of enlisting until KTx.

Methods:

Patients

65 years listed for transplantation at our centre

were asked to answer the SF36 questionnaire when accepted for the

waiting list and thereafter every 6th months until transplantation.

Results:

A total of 180 patients have been included from Jan 2013.

Mean age 70.6 years (65–82), 68.3% male. 75 and 39 patients

fulfilled the baseline + 6 months and baseline + 12 months

questionnaires. So far, 100 patients are transplanted. Compared to

the age-matched Norwegian population there were no difference

in SF36 scores at baseline. At baseline the mean score for social

function was significant lower for patients in dialysis compared to

patients not in dialysis. This difference was not significant after 6

and 12 months. Females had significant lower scores for vitality at

baseline and after 1 year.

Conclusion:

Our preliminary findings indicate that elderly patients

enlisted for KTx have no significant decrease in HRQOL during first

year on the waiting list and HRQOL is comparable to the normal

population.

O-077

Failure in osteoporosis management after hip fracture

G. Gavazzi

, B. Bonne

, L. Jose

, C. Bioteau

, J. Tonetti

, S. Drevet

University of Grenoble Alpes, Grenoble, France

Objectives:

Osteoporosis is a frequent disease with high mortality

and morbidity rates, especially after hip fracture. Anti-osteoporotic

drugs are efficient to reduce secondary osteoporotic fracture but

little is known on rates of prescription after hip fracture in France.

The goal of this study was to measure anti-osteoporotic drugs

therapy prescription over a 1-year period following a hip fracture,

the 1-year mortality and the readmission rate after the fracture.

Methods:

This retrospective cohort study in a large French urban

area recruited patients of 65 years old and older, hospitalized for

hip fracture between 1 July 2012 and 30 June 2013. Follow-up lasted

one year. Data concerning treatment were provided by public health

insurance agency.

Results:

Out of the 561 patients discharged for hip fracture, 367

were included and 345 were followed-up for 1 year. Over the 1-

year period, 15 patients [4.3%, 95% confidence interval (CI) 2.5–7.1%]

received antiresorptive drugs at any time, 51.6% (95% CI 46.2–

57.0%) and 16.5% (95% CI 12.8–20.9%) for vitamin D and calcium

respectively. During the 1-year follow-up period, 105 patients

(28.6%, 95% CI 24.3–33.5%) died. Readmissions have been reported

in 195 patients (56.5%, 95% CI 50.5–62.5%) in the year following the

fracture.

Conclusions:

Our findings indicate that anti-osteoporotic

treatments after hip fracture remains very low in France as the

mortality rate remains high over the first following year after

hip fracture. Reasons for reluctance of these treatments should

be considered in future studies.

Pre- and postoperative care

O-078

Muscle mass and postoperative recovery after major

oncological abdominal surgery

J. Dronkers

, R. Winkels

, M. van Zutphen

, E. Kampman

Gelderse Vallei Hospital, Ede, Netherlands;

Wageningen University,

Wageningen, Netherlands

Objectives:

Low muscle mass and related functional mobility and

physical activity affect the ability of a person to cope with major

abdominal surgery. The objective is to establish the association of

preoperative muscle mass with postoperative mortality after major

oncological abdominal surgery and to determine the relationship

between preoperative muscle mass and functional mobility and

physical activity.

Methods:

Prospective cohort study of 84 patients. Skeletal

muscle mass area (SMI) was determined by analyzing computer

tomography (CT) scans. Functional mobility was assessed as

“timed up-and-go” (TUG) and physical activity was assessed by

a questionnaire (LAPAQ).

Results:

Hazard Ratio (HR) for overall mortality was 1.55 (95% CI

0.83–2.88) for low SMI, 2.38 (95% CI 1.26–4.49) for low functional

mobility (TUG) and 1.92 (95% CI 1.20–3.05)for low physical activity

(LAPAQ). Correlation coefficients between SMI and TUG and LAPAQ

were −0.14 and 0.10, respectively and not significant. Subanalysis of

in-hospital mortality showed a HR of 0.80 (95% CI 0.19–3.36) for low

SMI, 4.18 (95% CI 1.55–11.24) for low functional mobility, and 3.13

(95% CI 0.99–9.89) for low activity. HR for post-discharge mortality

was 1.65 (95% CI 0.83–3.29) for low SMI, 1.53 (95% CI 0.75–3.11) for

low functional mobility and 1.60 (95% CI 0.95–2.69) for low activity

level.

Conclusion:

This study did not reveal a significant association

between muscle mass and overall mortality after major abdominal

oncological surgery. It seems that muscle is more associated with

the long term course of this patient group and functional mobility

and physical activity with the short-term in-hospital recovery.

O-079

Nutritional status as measured by the Mini Nutritional

Assessment Short Form as a predictor of hip fracture outcomes

M. Nuotio

, P. Tuominen

, T. Luukkaala

Sein¨ajoki Central Hospital, Sein¨ajoki, Finland;

Department of

Nutritional Therapy, Sein¨ajoki Central Hospital, Sein¨ajoki;

Science

Center, Pirkanmaa Hospital District and University of Tampere,

Tampere, Finland

Objectives:

We examined the association of nutritional status as

measured by the Mini Nutritional Assessment Short Form (MNA-SF)