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Oral presentations / European Geriatric Medicine 6S1 (2015) S5
–
S31
S11
respectively. For ≥80 years of age; cut-off points were SBPs
≤130mmHg, DBPs ≤70mmHg. Residents were evaluated for
orthostatic symptoms, current BPs and comprehensive geriatric
assessment.
Results:
69 were male (78%) and 19 were female (22%) from 88
eligible subjects. Mean age was 71.8+7.8 years. Supine systolic
and diastolic hypotension prevalences were 34.6% and 47.4%,
respectively. Ratios were 66.7% and 50% for ≥80 years of
aged (n = 18), respectively. OHT prevalence was 26%. 55% had
orthostatic symptoms. Most frequent symptom was dizziness on
standing-up (45.5%). Mini-Mental-State-Examination scores were
significantly lower in OHT group (26.4+3.7 vs 24.2+3.1; p
<
0.05).
‘Decreased attention’ symptom was significantly higher in OHT
group (n = 20/22 vs n = 30/45, p
<
0.05). At past BP examination,
systolic and diastolic hypotension ratios were 26% and 47.3% for
60–80 years of age and 73% and 49.3% for ≥80 years of aged,
respectively.
Conclusion:
Both supine hypotension and OHT are signifi-
cantly prevalent in ‘hypertensive’ nursing-home-residents on
antihypertensive-treatment and they are associated with impaired
cognition.
O-021
Cardiovascular comorbidity in 29 000 patients with different
dementia disorders
R. Dorota
1
, P. Cermakova
2
, J. Kristina
2
, J. Fastbom
3
, S. Garcia-Ptacek
2
,
B. Winblad
4
, L. Lund
2
, M. Eriksdotter
2
1
Karolinska Institutet, Stockholm, Sweden;
2
Karolinska Institutet,
Stockholm;
3
Aging Research Center, Stockholm, Sweden;
4
Karolinska
Institute, Stockholm, Sweden
Objectives:
Cardiovascular diseases are leading causes of death and
dementia patients are also affected by them. We aim to investigate
associations between different dementias and cardiovascular
diseases and determine their impact on mortality.
Methods:
This study included 29 630 patients from the Swedish
Dementia Registry SveDem (mean age 79 years, 59% women)
diagnosed with Alzheimer’s disease (AD), mixed dementia, vascular
dementia, dementia with Lewy bodies (DLB), Parkinson disease
dementia (PDD), frontotemporal dementia (FTD) or unspecified
dementia. Records of cardiovascular diseases come from the
Swedish National Patient Register. Multinomial logistic regression
and cox proportional hazard models were applied.
Results:
Compared to AD, we found a higher burden of
all cardiovascular diseases in mixed and vascular dementia.
Cerebrovascular diseases were more associated with DLB than with
AD. Diabetes mellitus was less associated with PDD and DLB than
with AD. Ischemic heart disease was less associated with PDD and
FTD than AD. All cardiovascular diseases predicted death in patients
with AD, mixed and vascular dementia. Only ischemic heart
disease significantly predicted death in DLB patients (HR = 1.72;
95% CI=1.16–2.55). In PDD patients, heart failure and diabetes
mellitus were associated with a higher risk of death (HR = 3.06;
95% CI=1.74–5.41 and HR = 3.44; 95% CI=1.31–9.03). In FTD patients,
ischemic heart disease and atrial fibrillation significantly predicted
death (HR = 2.11; 95% CI=1.08–4.14 and HR = 3.15; 95% CI=1.60–6.22,
respectively).
Conclusions:
Our study highlights differences in the occurrence
and prognostic significance of cardiovascular diseases in several
dementia disorders. This has implications for the care and
treatment of the different dementia disorders.
O-022
Increased risk of hip fracture in people with self-perceived
memory loss. A NOREPOS based prospective cohort study of
10449 individuals aged 67
–
78 years
M. Garcia Lopez
1
, T.K. Omsland
1
, A.J. Søgaard
2
, H.E. Meyer
2
1
Universitetet i Oslo/ Oslo University Hospital, Oslo, Norway;
2
Norwegian Institute of Public Health, Oslo, Norway
Objectives:
The purpose of this study was to examine the
prospective associations between self-reported memory-loss and
subsequent hip fracture.
Methods:
We obtained information on self-perceived memory loss
and confounders from three regional heath surveys performed in
Oslo and in two counties north of Oslo during 2000–2001. Four
questions concerning indicators of memory loss were included,
followed by a concluding question (asking if they considered
memory loss as a problem in daily life) which was selected as
exposure variable. We selected individuals 67–78 years old due to
low incidence of memory complaints at younger ages. A total of
10,449 men and women were followed for a median of 7.8 years.
Information on first hip fracture during follow up (a total number
of 565) was retrieved by linkage to the NOREPOS (Norwegian
Osteoporosis Epidemiologic Studies) hip fracture database.
Results:
The risk of having a hip fracture was higher in those
reporting memory loss as a problem for their daily life, with
a relative risk (RR) of 1.84 (95% CI 1.34–2.51) in woman and a
RR of 1.65 (95% CI 1.22–2.22) in men. After adjustment for possible
confounders (including: self-perceived general health state, drug
use, BMI and smoking) a significant association persisted, both in
women (RR 1.54, 95% CI 1.10–2.14) and in men (RR 1.42, 95% CI
1.04–1.93).
Conclusions:
Elderly reporting self-perceived memory loss have
higher risk of suffering a hip fracture than those who did
not report it. These possible important findings warrant further
investigations.
Acute care
O-023
The reality of a Portuguese Emergency Department (ED) post
fall evaluation: A retrospective analysis
L. Marques
Hospital Beatriz ˆAngelo, Lisboa, Portugal
Objectives:
This study aim is to characterize the population of
adults aged 65 or older seen in our ED after a fall and the respective
post fall management approach and follow up. Specific objectives
are to identify consequences of the fall, define if fall circumstances
were analysed, if fall risk factors were identified and if specific post
fall evaluation was prescribed.
Methods:
Retrospective observational study of routinely collected
data from a general ED over a 15 days period. Only adults aged 65
years or older presenting after a fall were included. Clinical files
were analysed and appropriate statistical analysis performed.
Results:
140 medical files were reviewed, 66% of the patients were
females, the median age was 80 years, 37% of the patients had
age between 75 and 84 years. The most common injuries related
to falls were fractures (34%). Only 13% of this ED visits resulted
in hospital admission, mainly due to fractures for Chirurgical
treatment (67%). In 57% of the clinical files there was no reference
to fall circumstances. Only 3 files had specific fall risk factors
identified. There was no gait and balance test performed in any
of the cases, nor specific orientation for post fall evaluation and
prevention.
Conclusions:
These results show that international recommenda-
tions for falls prevention and management in older persons are